Description

Grape Seed Extract OPC 300mg + Astaxanthin 3mg – Dual Antioxidant Protection for Cells, Vessels & Skin

Free radical damage is one of the most widely studied mechanisms in modern nutritional science. Reactive oxygen species — produced naturally by metabolism and amplified by environmental stressors such as UV radiation, pollution, processed foods and stress — are implicated in the progressive oxidative wear of cellular structures across virtually every tissue type. The body has its own antioxidant defence systems, but these can be overwhelmed, particularly with advancing age and increased environmental exposure.

Dr Gabriel’s® Grape Seed Extract OPC 300mg + Astaxanthin provides a scientifically coherent answer to this challenge — combining two complementary, high-potency antioxidants that work across different cellular compartments: OPC (water-soluble polyphenols from grape seed, active in aqueous environments) and Astaxanthin (a fat-soluble carotenoid, active in lipid membranes and lipoproteins). Together, they provide comprehensive antioxidant coverage that neither ingredient can deliver alone.

Ingredient 1 — Grape Seed Extract OPC (300mg, 64% OPC)

Grape Seed Extract (GSE) is derived from the seeds of Vitis vinifera grapes — a concentrated source of oligomeric proanthocyanidins (OPC), a class of polyphenolic flavonoids first extensively studied by French pharmacologist Professor Jack Masquelier in the 1940s and 1950s. OPC belong to the condensed tannin family and are among the most potent water-soluble antioxidants identified in nature.

The 64% OPC standardisation (verified by UV analysis) means that each 300mg capsule delivers 192mg of pure oligomeric proanthocyanidins — a meaningful, research-relevant dose in a single serving. This level of standardisation distinguishes a pharmaceutical-grade extract from generic grape seed powder of variable and often unstated OPC content.

Ingredient 2 — Astaxanthin (3mg, from Haematococcus pluvialis)

Astaxanthin is a naturally occurring xanthophyll carotenoid — a fat-soluble red-pink pigment produced by the freshwater microalgae Haematococcus pluvialis as a survival mechanism against intense UV radiation and nutrient stress. It is the pigment responsible for the characteristic red-pink colour of salmon, flamingos and crustaceans.

Astaxanthin is classified as one of the most potent lipid-soluble antioxidants identified in nature, with a unique molecular structure that allows it to span the full width of a cell membrane — providing antioxidant protection on both the interior and exterior faces simultaneously. This structural property is not shared by most other fat-soluble antioxidants including beta-carotene and vitamin E.

Why Combine OPC and Astaxanthin? — The Dual-Phase Antioxidant Logic

Active Ingredient Profile — Per Capsule

Who Is This Product For?

• Adults 40–65 seeking comprehensive antioxidant support for cardiovascular wellness and normal vascular function
• Skin-focused buyers (primarily female, 35–55) who want to support normal skin elasticity and collagen structure from within — the OPC + skin collagen connection is one of the most searched beauty-supplement topics in AT/DE
• Active adults and sports enthusiasts seeking antioxidant support for post-exercise cellular recovery
• Health-conscious consumers building an antioxidant stack alongside other Dr Gabriel’s products
• Adults who have researched OPC or astaxanthin individually and are looking for a combined formula that reduces daily supplement count

FAQ 

What is OPC in Grape Seed Extract?

OPC stands for Oligomeric Proanthocyanidins — a class of water-soluble polyphenolic antioxidants found in exceptionally high concentrations in grape seeds. They are condensed tannins composed of catechin and epicatechin units, and are among the most potent free radical scavengers identified in plant sources. The 64% OPC standardisation in this product means each 300mg capsule delivers 192mg of pure OPC — a clinically meaningful dose in a single serving.

How does Grape Seed Extract benefit skin?

Grape Seed OPC interacts with collagen and elastin — the structural proteins that give skin its firmness, elasticity and smooth texture. OPC stabilise collagen crosslinks and protect elastin from degradation by oxidative enzymes. This biochemical relationship with skin structural proteins is one of the most studied aspects of OPC in nutritional science. As a food supplement, Grape Seed OPC supports normal skin collagen structure — it does not treat diagnosed skin conditions.

Can OPC support cardiovascular health?

OPC are among the most studied polyphenol compounds in relation to vascular function. They support normal microvascular integrity by interacting with collagen and elastin in capillary walls, and contribute to antioxidant protection of LDL particles from oxidative damage — a mechanistic step widely studied in cardiovascular nutrition research. As food supplements, OPC contribute to antioxidant support for the cardiovascular system — they do not treat or prevent cardiovascular disease.

What is the difference between OPC from grape seed and resveratrol?

Both OPC (oligomeric proanthocyanidins) and resveratrol are polyphenols from Vitis vinifera grapes, but they are structurally distinct compounds. OPC are condensed tannins found primarily in grape seeds, with potent water-soluble antioxidant properties and documented interaction with structural proteins (collagen, elastin). Resveratrol is a stilbene found primarily in grape skin, researched for different cellular signalling pathways (sirtuins, AMPK). They are complementary, not interchangeable.